Blackmailing a new couple to aid with his experiments the Baron, desperate for data that is vital, abducts a person from an insane asylum. On route the abductee dies and his assistant and the Baron transplant his brain. The monster is tormented by way of a soul in an casing as well as after a visit for his wife who violently rejects his massive form, the monster wreaks his revenge on the perpetrator of his own distress: Baron Frankenstein.